Are you DEPRESSED because you're
alone and no one loves you?
The Big Bang Theory Season 4, Episode 5
Well, not so much DEPRESSED
as lonely.
The Big Bang Theory Season 4, Episode 22
...because I'm fun,
I'm not clinically DEPRESSED at all.
The Big Bang Theory Season 6, Episode 5
He's DEPRESSED because he's pathetic
and creepy and can't get girls.
The Big Bang Theory Season 2, Episode 12
Blue, as in DEPRESSED.
The Big Bang Theory Season 4, Episode 22